People with PAD have greater risk

Technology / Applications


Evaluation by ArterioVision

Principle and Definition

ArterioVision MS-3000 is a computer-based non-invasive system with the ability to determine Ankle Brachial Index (ABI) for assessment of lower extremity stenosis and Arterial Stiffness Index (ASI) for assessment of the degree of arterial stiffness using the oscillometric method.

Excessive stress and lack of exercise are known as health risk factors that trigger progression of certain life-threatening diseases. ArterioVision MS-3000 provides an opportunity to assess such risk factors.

ASI assessment with ArterioVision MS-3000 is based on measurable physiological phenomena observed from the elasticity and hardness of the artery using pressure and volumetric changes. The principle of ASI measurement was established following a proposal by Professor Hideaki Shimazu at Kyorin University, and ArterioVision MS-3000 is the original and peerless device.

ArterioVision MS-3000 is the product of more than two decades of intensive research. Its method of measuring can be easily applied in almost all medical fields. ArterioVision MS-3000 provides an opportunity to manage the effect of health enhancement strategy.

How to Measure

MS-3000 measures blood pressure and pulse wave using cuffs wrapped around the extremities in the supine position and calculate ABI and ASI. The measurement will be completed in approximately 5 minutes. The results will be recorded in the Software, and ABI and ASI will be calculated.


MS-3000 offers Ankle Brachial Index (ABI) and Arterial Stiffness Index (ASI) as indicators for assessment of arterial stiffness for healthcare professionals. These measurements allow speedy and objective analysis of vascular function. Such data can provide valuable information to healthcare professionals. (Data may be used to determine whether to start treatment in patients without any noticeable symptoms or clinical signs.)

While a healthy heart efficiently supplies oxygen and nutrients throughout the body, it also sends waste to the kidneys, liver and lungs for removal. For this to occur, arteries must be in good condition. Arteries may become atherosclerotic, arteriosclerotic or stiffened (due to reduced elasticity and increased stenosis) over time. These changes will cause strain on the heart, valves and arteries, which may cause stroke, heart attack, renal failure and/or sudden death.

About ASI

ASI measures whether the vascular system is functioning normally without any limitations due to health risks. Arterial stiffness due to medial calcification and reduced elasticity caused by aging is the most critical factor contributing to increase in ASI. Unlike other measuring principles for arterial stiffness, ASI allows efficient assessment of arterial stiffness directly under a cuff, thus making it e a useful index for assessing arterial stiffness in each extremity.

About ABI

ABI is an index to assess peripheral arterial diseases (P.A.D.) such as stenosis/occlusion of leg arteries. It is calculated by dividing systolic blood pressure of the right and left ankles by that of upper arm (right or left, whichever higher).

About PWV

PWV measures stiffness of artery by calculating of the velocity of heat beat. Pulsation caused by blood extruded from the heart reaches the periphery of limbs through the walls and blood in artery.
Property like vascular walls is generally slow in transmission when soft. In contrary, the property of transmitting is fast when hard. For this reason, pulsation is transmitted fast in hard vessels where the arteriosclerosis progresses and the elasticity of the arterial wall are lost.

Pulse wave propagation speed (PWV) is calculated by fitting the pressure band of the blood pressure monitor on both arms and ankle, measuring the distance between sensors and the time required to reach the pulse wave. The higher the value, the more arteriosclerosis is progressing.


Peripheral Artery Disease (PAD) reduces a life prognosis and patient QOL. The greatest cause of death in PAD is coronary artery disease (CAD), but arteriosclerotic disease is merged, which lowers body function and decreases patient QOL. It is important to know and eliminate CAD risks when managing PAD.

ArterioVision MS-3000 enables highly accurate diagnosis by combining indices obtained by its measurements.

PAD Diagnosis

PAD will be diagnosed by % MAP and Upstroke Time obtained from PVR and ABI.

CAD Risk Screening

CAD risk will be diagnosed by baPWV and Brachial ASI. For PAD patients with ABI less than 1.0, baPWV treats the measured value as a reference, but since ASI is not affected by PAD in principle, it can be evaluated as an independent index.


ArterioVision MS-3000 is very user-friendly and intuitively operable for both health professionals and related care providers. Due to its simple hardware and standard computer requirements, ArterioVision MS-3000 can be smoothly incorporated into virtually any of medical- and health-related facilities such as clinics, laboratories, health clubs and wellness centers.
ArterioVision MS-3000 can also be used easily in regular health checkups. Assessment results may be used in regular health maintenance, or monitoring general health conditions or effects of various therapies to achieve intended health conditions. ArterioVision MS-3000 helps in reducing the incidence of profession- or semi-professional work related diseases in affiliated staffs throughout the various departments of treatment.

Clinical Departments

Preventiver Medicine
Compression therapy and wound care management
Endovascular Surgery


General practitioner
Clinical investigators
Stress management counselors
Alternative practitioner
Biofeedback therapists
Physiology teacher/lecturers
Physical/occupational/recreational therapists
Cardiovascular rehabilitation specialists